↗ public sourceswww.adisseo.com/eu/products/adimix-precision· 3 studies, 3 independent/mixed
Evidence · moderate
The active substance is backed by 3 studies including meta-analyses; the verdict per claim below reflects what the literature actually shows, not the brochure. Strength reflects the active substance, not the brand.
What the manufacturer claims
Free
Captured from the product page, typed and attributed — the producer’s own statements, checked against the literature below.
Physiological
Targeted butyrate delivery that strengthens the gut barrier, supports gut development and promotes a controlled inflammatory response
Safety
Reduces foodborne pathogens (Salmonella, Campylobacter) by supporting a balanced microbiota (zoonoses control/food safety)
Performance
Improves intestinal function, nutrient utilisation and performance
Manufacturer’s own words — not independently verified. The ledger below gives the evidence verdict for each.
Claim ↔ evidence ledger
Verdict free · receipts in Power
Each claim against the studies on the active substance, with the funding split. Open a row for the studies behind the verdict.
Claim
Verdict
Evidence & funding
PhysiologicalTargeted butyrate delivery that strengthens the gut barrier, supports gut developmen…
Supported
1 study · 100% indep
›
Read Gut-barrier reinforcement is independently supported, most clearly under challenge.
2022
Protected sodium butyrate (MCFA-salt coated) reinforces the gut barrier in coccidiosis-challenged broilers0.5-1 kg/t maintained mucin-secretory cells; 1 kg/t restored goblet cells, morphometry and microbiota and improved the intestinal immune system under coccidiosis
SafetyReduces foodborne pathogens (Salmonella, Campylobacter) by supporting a balanced mic…
Mixed
1 study · 100% indep
›
Read Pathogen/microbiota effects are context-dependent; one model found only limited microbiota impact.
2022
Coated butyrate vs salinomycin in a broiler gut-leakage (enteric challenge) modelCoated butyrate (500 mg/kg) had only limited effects on broiler microbiota, whereas salinomycin improved microbiota and performance
Why these studies The evidence for a proprietary product is the evidence for its active substance. These are the studies (meta-analyses first) behind the verdicts above, with funding labelled.
Year
Study & effect size
Funding
Type
Access
2022
Protected sodium butyrate (MCFA-salt coated) reinforces the gut barrier in coccidiosis-challenged broilers0.5-1 kg/t maintained mucin-secretory cells; 1 kg/t restored goblet cells, morphometry and microbiota and improved the intestinal immune system under coccidiosis
Coated butyrate vs salinomycin in a broiler gut-leakage (enteric challenge) modelCoated butyrate (500 mg/kg) had only limited effects on broiler microbiota, whereas salinomycin improved microbiota and performance
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Analysis & tools
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Open the analyst workbench
Dose benchmark, the independent-vs-sponsored split, the pooled meta-analysis effects, the contradictions and the gaps — all derived from the studies above.
Dose: label vs effective trial range vs EU max
Independence-of-evidence breakdown
Pooled meta-analysis effect sizes
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Dose benchmark
Label / recommended≈0.5-2 kg/t
Effective in trials0.5-2 kg/t (0.5-1.5 g/kg typical)
EU maximumGoverned by sensory good-practice use
Coating targets distal release; benefit is clearest under enteric/coccidial challenge.
Adimix Precision is a coated sodium butyrate (~30%) designed for targeted gut delivery in poultry and pigs.
Independent trials show it reinforces the gut barrier (mucin/goblet cells, morphometry), most clearly under coccidiosis/necrotic-enteritis challenge.
The pathogen-control (Salmonella/Campylobacter) and performance claims are context-dependent — one model found only limited microbiota effects versus a coccidiostat.
Benefits are typically smaller in unchallenged, well-managed flocks.
Regulatory note: sodium butyrate is an EU sensory (flavouring) additive, so the gut-health/zoonoses positioning is a functional claim and the coating is a delivery technology.
Where studies disagree: Benefits are often not detected in unchallenged, well-managed birds, and one head-to-head gut-leakage model found coated butyrate had only limited microbiota effects compared with a coccidiostat — so the pathogen-control and performance claims are conditional.
Gaps: No product-specific meta-analysis captured. Salmonella/Campylobacter reduction is supported at the butyrate-class level rather than by a dedicated Adimix field trial here. No product-specific patent captured.
Manufacturer’s stated mechanism (their words): A coated sodium butyrate designed to release butyrate in a targeted way along the gut, where it serves as enterocyte energy, reinforces the intestinal barrier (mucin/goblet cells, tight junctions), promotes a controlled inflammatory response and helps suppress foodborne pathogens (Salmonella, Campylobacter).
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Put this beside alternatives on the same active substance (e.g. HMBi / other rumen-protected methionine), and take the data with you.
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