↗ public sourceswww.actifeed.com/klinofeed.html· 5 studies, 4 independent/mixed
Evidence · moderate
The active substance is backed by 5 studies including meta-analyses; the verdict per claim below reflects what the literature actually shows, not the brochure. Strength reflects the active substance, not the brand.
What the manufacturer claims
Free
Captured from the product page, typed and attributed — the producer’s own statements, checked against the literature below.
Safety
Acts as a detoxifier and is effective against mycotoxins (e.g. aflatoxin)
Environmental
Selectively adsorbs the ammonium ion and controls odours
Zootechnical effects on growth and reproduction and benefit in digestive disorders (piglets) and rumen dysfunction
Manufacturer’s own words — not independently verified. The ledger below gives the evidence verdict for each.
Claim ↔ evidence ledger
Verdict free · receipts in Power
Each claim against the studies on the active substance, with the funding split. Open a row for the studies behind the verdict.
Claim
Verdict
Evidence & funding
SafetyActs as a detoxifier and is effective against mycotoxins (e.g. aflatoxin)
Mixed
3 studies · 67% indep
›
Read Mycotoxin-binding/performance protection is supported by a meta-analysis and RCTs — but this is NOT the EU-authorised function.
2025
Evaluating zeolite stability as a mycotoxin binder in broiler chickens' growth performance: a meta-analysisZeolite improved ADG, DFI and FCR in mycotoxin-exposed broilers (Hedges g' > 0.8, P<0.01); clinoptilolite cut FCR and mortality (g' > |0.8|)
Preventive efficacy of clinoptilolite in broilers during chronic aflatoxin (50 and 100 ppb) exposureClinoptilolite 15 g/kg moderately reduced the body-weight loss caused by 100 ppb aflatoxin
Effects of modified clinoptilolite (Minazel Plus) on aflatoxin B1 and ochratoxin A detoxification and performance in broilersModified clinoptilolite 1 g/kg reduced AFB1/OTA gastrointestinal absorption and protected performance
EnvironmentalSelectively adsorbs the ammonium ion and controls odours
Supported
1 study · 100% indep
›
Read Ammonium adsorption and lower aerial ammonia are supported by the ion-exchange mechanism and pig data.
2002
Mineral binders and zeolites — nitrogen excretion shift and aerial ammonia (review within a clinoptilolite/aflatoxin study)Zeolites shift nitrogen excretion from urine to faeces in monogastrics, lowering aerial ammonia in housing
Binder/anti-caking efficacy is accepted by EFSA (the authorised function) but was not the subject of the captured animal trials.
PerformanceZootechnical effects on growth and reproduction and benefit in digestive disorders (…
Supported
1 study · 100% indep
›
Read Gut/anti-diarrhoea effects supported; broad growth/reproduction benefits were called 'partly controversial' by EFSA (2013).
2019
Effects of clinoptilolite and modified clinoptilolite on growth performance, intestinal microflora and gut parameters of broilersLowered caecal E. coli and Salmonella counts and improved gut parameters vs control
Bottom line. Clinoptilolite is an EU-authorised technological additive — but only as a binder and anti-caking agent (max 1%), not as the mycotoxin/ammonium/zootechnical product the page describes.
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Composition
Free
● Disclosed by manufacturer
clinoptilolite content — ≥80% clinoptilolite, ≤20% clay minerals (sedimentary origin)active mineral (per EFSA characterisation of the authorised additive)
Why these studies The evidence for a proprietary product is the evidence for its active substance. These are the studies (meta-analyses first) behind the verdicts above, with funding labelled.
Year
Study & effect size
Funding
Type
Access
2025
Evaluating zeolite stability as a mycotoxin binder in broiler chickens' growth performance: a meta-analysisZeolite improved ADG, DFI and FCR in mycotoxin-exposed broilers (Hedges g' > 0.8, P<0.01); clinoptilolite cut FCR and mortality (g' > |0.8|)
Preventive efficacy of clinoptilolite in broilers during chronic aflatoxin (50 and 100 ppb) exposureClinoptilolite 15 g/kg moderately reduced the body-weight loss caused by 100 ppb aflatoxin
Effects of clinoptilolite and modified clinoptilolite on growth performance, intestinal microflora and gut parameters of broilersLowered caecal E. coli and Salmonella counts and improved gut parameters vs control
Mineral binders and zeolites — nitrogen excretion shift and aerial ammonia (review within a clinoptilolite/aflatoxin study)Zeolites shift nitrogen excretion from urine to faeces in monogastrics, lowering aerial ammonia in housing
Effects of modified clinoptilolite (Minazel Plus) on aflatoxin B1 and ochratoxin A detoxification and performance in broilersModified clinoptilolite 1 g/kg reduced AFB1/OTA gastrointestinal absorption and protected performance
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Analysis & tools
◆ Power
The working map a maker won’t give you — built only from the evidence on this page. Nothing here is marketing.
◆ Power view
Open the analyst workbench
Dose benchmark, the independent-vs-sponsored split, the pooled meta-analysis effects, the contradictions and the gaps — all derived from the studies above.
Dose: label vs effective trial range vs EU max
Independence-of-evidence breakdown
Pooled meta-analysis effect sizes
Compare · CSV / JSON · API
Dose benchmark
Label / recommendedNot numerically stated
Effective in trials1-15 g/kg in mycotoxin/aflatoxin trials
EU maximum10,000 mg/kg (1%) complete feed (binder/anti-caking authorisation)
Mycotoxin-binding inclusion in trials often exceeds the authorised binder level.
Pooled estimates from the systematic reviews/meta-analyses above — the closest thing to a settled answer.
Discussion — grounded in the evidence
Clinoptilolite is an EU-authorised technological additive — but only as a binder and anti-caking agent (max 1%), not as the mycotoxin/ammonium/zootechnical product the page describes.
Independent evidence, including a 2025 meta-analysis, supports mycotoxin (aflatoxin/ochratoxin) binding that restores growth and lowers FCR in challenged broilers.
The ammonium-adsorption and lower-aerial-ammonia claims are supported by a well-established ion-exchange mechanism and pig data.
Gut and anti-diarrhoea effects in pigs/poultry are supported via pathogen/enterotoxin sequestration; broad growth/reproduction claims are weaker and were called controversial by EFSA.
EFSA also flags clinoptilolite as a skin/respiratory sensitiser with a nanoscale particle fraction — a user-safety, not animal, concern.
Where studies disagree: The product is marketed as a mycotoxin detoxifier, but its EU authorisation covers only binder/anti-caking — clinoptilolite of sedimentary origin is not authorised in the mycotoxin-reduction group. EFSA (2013) judged broad growth/reproduction effects 'partly controversial', whereas the page presents them as established.
Gaps: No independent trial of Klinofeed specifically, nor verification of its claimed 'activation' process. Binder/anti-caking efficacy (the authorised function) is accepted but not separately demonstrated in the captured studies.
Manufacturer’s stated mechanism (their words): A microporous (4 Å) sedimentary clinoptilolite with high cation-exchange capacity that selectively adsorbs ammonium and binds mycotoxins/toxins in the gut, and physically improves pellet durability, press yield and flowability; essentially not absorbed and excreted in faeces.
Compare & export
Put this beside alternatives on the same active substance (e.g. HMBi / other rumen-protected methionine), and take the data with you.
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