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Zootechnical additives · chickens for fattening, pigs
Signis
Brand Signis · Manufacturer AB Vista (AB Agri Ltd)
↗ public sourceswww.abvista.com/products/signis· 3 studies, 0 independent/mixed
Evidence · moderate
The active substance is backed by 3 studies including meta-analyses; the verdict per claim below reflects what the literature actually shows, not the brochure. Strength reflects the active substance, not the brand.
What the manufacturer claims
Free
Captured from the product page, typed and attributed — the producer’s own statements, checked against the literature below.
Physiological
A 'stimbiotic' that accelerates development of a fibre-degrading microbiome and increases fibre fermentation (short-chain fatty acids)
Performance
Improves weight gain and feed efficiency, including in energy-reduced diets
Economic
Allows reduced dietary energy and lower feed cost at maintained performance
Manufacturer’s own words — not independently verified. The ledger below gives the evidence verdict for each.
Claim ↔ evidence ledger
Verdict free · receipts in Power
Each claim against the studies on the active substance, with the funding split. Open a row for the studies behind the verdict.
Claim
Verdict
Evidence & funding
PhysiologicalA 'stimbiotic' that accelerates development of a fibre-degrading microbiome and incr…
Mixed
2 studies · 0% indep
›
Read Mechanism (more caecal SCFA, better fibre retention) supported; effects not always additive between XOS and xylanase.
2023
Broiler chicken response to xylanase and fermentable xylo-oligosaccharide supplementationStimbiotic improved FCR and weight gain (21-35 d and 0-35 d, P<0.05); increased NDF retention and caecal short-chain fatty acids
Effects of supplemental xylanase and xylo-oligosaccharides on production performance and gut-health variables of broiler chickensCombining xylanase and XOS increased average daily gain and altered caecal microbiota/SCFA versus control
PerformanceImproves weight gain and feed efficiency, including in energy-reduced diets
Supported
1 study · 0% indep
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Read Performance benefit clearest in energy-reduced diets; key trial is manufacturer-authored.
2021
Evaluation of xylanase and a fermentable xylo-oligosaccharide on performance and ileal digestibility of broilers fed energy- and amino-acid-deficient diets (Gonzalez-Ortiz et al.)Stimbiotic improved EPEF and FCR (P<0.001) regardless of energy/AA reduction; weight-gain gain greatest on the most energy-reduced diet (+451 g/bird)
EconomicAllows reduced dietary energy and lower feed cost at maintained performance
Mixed
no study
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Energy/cost-reduction claim is inferred from energy-reduced-diet trials, not from an economic study.
IndependentMixedIndustryNone/undisclosed
Bottom line. The 'stimbiotic' (xylanase + xylo-oligosaccharide) is a class AB Vista helped define; trials show it raises caecal short-chain fatty acids and improves fibre retention.
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Evidence — on the active substance
Table free · full-text in Power
Why these studies The evidence for a proprietary product is the evidence for its active substance. These are the studies (meta-analyses first) behind the verdicts above, with funding labelled.
Year
Study & effect size
Funding
Type
Access
2021
Evaluation of xylanase and a fermentable xylo-oligosaccharide on performance and ileal digestibility of broilers fed energy- and amino-acid-deficient diets (Gonzalez-Ortiz et al.)Stimbiotic improved EPEF and FCR (P<0.001) regardless of energy/AA reduction; weight-gain gain greatest on the most energy-reduced diet (+451 g/bird)
Broiler chicken response to xylanase and fermentable xylo-oligosaccharide supplementationStimbiotic improved FCR and weight gain (21-35 d and 0-35 d, P<0.05); increased NDF retention and caecal short-chain fatty acids
Effects of supplemental xylanase and xylo-oligosaccharides on production performance and gut-health variables of broiler chickensCombining xylanase and XOS increased average daily gain and altered caecal microbiota/SCFA versus control
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Analysis & tools
◆ Power
The working map a maker won’t give you — built only from the evidence on this page. Nothing here is marketing.
◆ Power view
Open the analyst workbench
Dose benchmark, the independent-vs-sponsored split, the pooled meta-analysis effects, the contradictions and the gaps — all derived from the studies above.
Dose: label vs effective trial range vs EU max
Independence-of-evidence breakdown
Pooled meta-analysis effect sizes
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Dose benchmark
Label / recommended~100 g/tonne complete feed
Effective in trials~100 g/t (100 g/t = quoted inclusion in trials)
EU maximumset by the authorised xylanase component
Stimbiotic is a low-inclusion priming dose, not an enzyme-activity dose.
The 'stimbiotic' (xylanase + xylo-oligosaccharide) is a class AB Vista helped define; trials show it raises caecal short-chain fatty acids and improves fibre retention.
Feed-efficiency and weight-gain benefits are real in the studies captured but are clearest in energy-reduced diets and the pivotal trial is manufacturer-authored.
There is as yet no independent meta-analysis on stimbiotics, so the strength of evidence is moderate rather than strong.
The energy/cost-reduction claim is inferred from energy-reduced-diet trials rather than from a dedicated economic study.
The xylanase component is EU-authorised; the regulatory status of the 'stimbiotic' composition should be confirmed in the EU Register.
Where studies disagree: XOS and xylanase benefits are not consistently additive; the largest performance gains appear specifically on energy-reduced diets rather than already-adequate diets.
Gaps: No published meta-analysis specific to 'stimbiotics' yet. Most positive trials are manufacturer-authored; fully independent replication is still limited. Swine and economic-return claims are less well documented than broiler performance.
Manufacturer’s stated mechanism (their words): A small priming dose of xylo-oligosaccharides plus xylanase selects for and accelerates a xylan/fibre-fermenting caecal microbiome, increasing short-chain fatty acid production from otherwise indigestible fibre ('stimbiotic' concept).
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Put this beside alternatives on the same active substance (e.g. HMBi / other rumen-protected methionine), and take the data with you.
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